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Lisa Shin Associate Professor of Psychology Ph.D.,
Harvard University, 1997
lisa.shin@tufts.edu
Dr. Shin received a Bachelor of
Arts degree in Psychology at Dartmouth
College and a PhD in Psychology at Harvard University. She
completed a
post-doctoral fellowship at the Massachusetts General
Hospital/Harvard
Medical School and has been a faculty member at Tufts since
1998.
Dr. Shin’s research involves examining brain function and
cognitive processing in patients with anxiety disorders,
especially posttraumatic stress disorder (PTSD). Specifically,
she uses positron emission tomography (PET) and functional
magnetic resonance imaging (fMRI) to study brain function while
patients perform attention and memory tasks in the scanner. The
goal of this research is to determine whether brain structures
such as the amygdala, medial prefrontal cortex, and hippocampus
function normally in patients with PTSD. Evidence thus far
suggests that in PTSD, the amygdala is hyperresponsive and
medial prefrontal cortex is hyporesponsive to threat-related
stimuli. Dr. Shin and her colleagues are currently conducting
studies to determine whether their functional neuroimaging
measures can help predict response to treatment. Her research
interests also include studying the neural mechanisms underlying
the processing of emotional information (e.g., facial
expressions, emotional words and pictures) in healthy
individuals.
Undergraduate or graduate students who are interested in working
in this lab should send an email message to Dr. Shin (lisa.shin@tufts.edu). |
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Representative Publications
Shin, LM, Rauch, S.L., & Pitman, RK. (2006). Amygdala, medial
prefrontal cortex, and hippocampal function in PTSD. Annals of
the New York Academy of Sciences,1071, 67-79.
Shin, L.M., Wright, C.I., Cannistraro, P., Wedig, M., McMullin,
K., Martis, B., Macklin, M.L., Lasko, N.B., Cavanagh, S.,
Krangel, T.S., Orr, S.P., Pitman, R.K., Whalen, P.J., & Rauch, S.L.
(2005). A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly
presented fearful faces in posttraumatic stress disorder.
Archives of General Psychiatry, 62, 273-281.
Shin, L.M., Orr, S.P., Carson, M.A., Rauch, S.L., Macklin, M.L.,
Lasko, N.B., Marzol Peters, P., Metzger, L.J., Dougherty, D.D.,
Cannistraro, P.A., Alpert, N.M., Fischman, A.J., & Pitman, R.K.
(2004). Regional cerebral blood flow in amygdala and medial
prefrontal cortex during traumatic imagery in male and female
Vietnam veterans with PTSD. Archives of General Psychiatry, 61,
168-176.
Shin, L.M., Shin, P.S., Heckers, S., Krangel, T.S., Macklin, M.L.,
Orr, S.P., Lasko, N.B., Segal, E., Makris, N., Richert, K.,
Levering, J., Schacter, D.L., Alpert, N.M., Fischman, A.J.,
Pitman, R.K. & Rauch, S.L. (2004). Hippocampal function in
posttraumatic stress disorder. Hippocampus, 14, 292-300.
Shin, L.M., Whalen, P.J., Pitman, R.K., Bush, G., Macklin, M.L.,
Lasko, N.B., Orr, S.P., McInerney, S.C., & Rauch, S.L. (2001).
An fMRI study of anterior cingulate function in posttraumatic
stress disorder. Biological Psychiatry, 50, 932-942.
Shin, L.M., Rauch, S.L., & Pitman, R.K. (2001). Symptom
provocation studies: The example of anxiety disorders. In
Dougherty, D. & Rauch, S.L. (Eds). Psychiatric neuroimaging
research: contemporary strategies (pp.101-124). Washington DC:
American Psychiatric Press.
Shin, L.M., Dougherty, D., Macklin, M.L., Orr, S.P., Pitman, R.K.,
& Rauch, S.L. (2000). Activation of anterior paralimbic structures
during guilt-related script-driven imagery. Biological
Psychiatry, 48, 43-50.
Rauch, S.L., Whalen, P.J., Shin, L.M., McInerney, S.C., Macklin,
M.L., Lasko, N.B., Orr, S.P., & Pitman, R.K. (2000). Exaggerated amygdala response to masked fearful vs. happy facial stimuli in
posttraumatic stress disorder: A functional MRI study.
Biological Psychiatry, 47, 769-776.
Shin, L.M., McNally, R.J., Kosslyn, S.M., Thompson, W.L., Rauch,
S.L., Alpert, N.M., Metzger, L.J., Lasko, N.B., Orr, S.P., &
Pitman, R.K. (1999). Regional cerebral blood flow during
script-driven imagery in childhood sexual abuse-related
posttraumatic stress disorder: A positron emission tomographic
investigation. American Journal of Psychiatry, 156, 575-584.
Shin, L.M., Kosslyn, S.M., McNally, R.J., Alpert, N.M.,
Thompson, W.L., Rauch, S.L., Macklin, M.L., & Pitman, R.K.
(1997). Visual imagery and perception in posttraumatic stress
disorder: A positron emission tomographic investigation.
Archives of General Psychiatry, 54, 233-241.
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