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| Name: |
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Kelly A. McLaughlin |
| Title: |
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Associate Professor of Biology
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| Departmental Affiliation: |
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Biology Department
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| Degrees: |
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Ph.D., University of Massachusetts at Amherst
B.S., Wheaton College |
| Expertise: |
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Molecular and Cell Biology/Developmental Biology, The processes leading to nephrogenesis and organ formation during development.
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| Major Awards: |
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National Kidney Foundation Fellowship, Bunting Fellowship from Radcliffe Institute for Advanced Study at Harvard University, National Research Service Award from National Institute of Health, Certificate of Distinction in Teaching, Harvard University and Radcliffe College, National American Heart Association: Scientist Development Grant |
| E-mail: |
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kelly.mclaughlin@tufts.edu
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| Other websites: |
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http://ase.tufts.edu/biology/faculty/mclaughlin
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| Scholarship & Research: |
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Bracken, C., Mizeracka, K.*, and McLaughlin, K.A. (2008) Patterning the embryonic kidney: BMP signaling mediates the differentiation of the pronephric tubules and duct. Developmental Dynamics 237:132–144 (published online Dec. 10, 2007).
Lenkowski, J., Reed, J.M., Deininger, L.*, and McLaughlin, K.A. (2008) Perturbation of Organogenesis by the Herbicide Atrazine in the Amphibian Xenopus laevis. Environmental Health Perspectives 116:223-230 (published online Nov. 22, 2007).
Contakos, S. P., Gaydos, C., Pfeil, E.C., and McLaughlin, K.A. Subdividing the embryo: a role for Notch signaling during germ layer patterning in Xenopus laevis. Developmental Biology: (in press 2005).
Van Stry, M., McLaughlin, K.A., Ataliotis, P.,and Symes, K. (2004). The mitochondrial-apoptotic pathway is triggered in Xenopus mesoderm cells deprived of PDGF receptor signaling during gastrulation. Developmental Biology Apr 15; 268(1): 232-42.
Tonomura, N., McLaughlin, K. A., Grimm, L., Goldsby, R. A., and Osborne, B. A.; (2003) Glucocorticoid-induced Apoptosis of Thymocytes: Requirement of Proteasome Dependent Mitochondrial Activity. Journal of Immunology. 170(5):2469-78.
Rones, M. S., Woda, J., Mercola, M., and McLaughlin, K. A. (2002). Isolation and Characterization of Xenopus Hey-1: A Downstream Mediator of Notch Signaling. Developmental Dynamics. 225: 554-560.
McLaughlin, K. A., Rones, M. S., and Mercola, M. (2000). Notch regulates cell fate in the developing pronephros. Developmental Biology. 227, 567-580.
Rones, M. S., McLaughlin, K. A., Raffin, M., and Mercola, M. (2000). Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis. Development.127, 3865-3876.
McLaughlin, K. A., Smith, S., Milligan, C., Bielke, W., Schwartz, L. M., and Osborne, B. A. (1996). "The isolation and characterization of cell death genes." In: Weir's Handbook for Experimental Immunology. Blackwell Science, Inc., Boston, MA.
Liu, Z.-G., Smith, S., McLaughlin, K. A., Schwartz, L. and Osborne, B.A. (1994). Apoptotic signals delivered through the T cell receptor of T cell hybrid require the immediate-early gene nur77. Nature. 367:281-284.
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