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| Name: |
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David Walt |
| Title: |
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Robinson Professor of Chemistry
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| Departmental Affiliation: |
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Chemistry Department
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| Degrees: |
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Ph.D., 1979 SUNY at Stony Brook; B.S., 1974 University of Michigan at Ann Arbor; Postdoctoral, 1979 MIT |
| Expertise: |
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Materials Chemistry
Analytical Chemistry
Bioorganic Chemistry
Application of enzymes and cells to organic synthesis; enzyme mechanistic studies; preparation of fiber optic chemical sensors; immunochemistry, polymeric microstructures, artificial sensing systems, combinatorial chemistry.
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| Major Awards: |
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Biosensors and Bioeletronic Award, NSF Special Creativity Award, 3M Creativity Award |
| E-mail: |
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david.walt@tufts.edu
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| Other websites: |
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http://www.chem.tufts.edu/faculty/walt/index.html
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| Scholarship & Research: |
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“Simultaneous Monitoring Gene Expression Kinetics and Genetic Noise in Single Cells by Optical Well Arrays,” Yina Kunag, Israel Biran, and David R. Walt, Analytical Chemistry, 76, pp. 6282-6286 (2004).
“Fabrication of Gold Microtubules and Microwires in High Aspect Ratio Capillary,” David J. Monk, and David R. Walt, Journal of American Chemical Society, 126, pp.11416-11417 (2004).
“Optical fiber-based biosensors,” David J. Monk, and David R. Walt, Anal. Bioanal. Chem., 379, pp. 931-945 (2004).
“Increasing lifetimes of fiber-optic sensor arrays for chemical warfare detection,” Sandra Bencic, and David R. Walt, Proc. SPIE-Int. Soc. Opt. Eng., 5269, pp.83-88 (2004).
“Microsphere-based DNA biosensor,” Linan Song, Jason Epstein, and David R. Walt, Proc. SPIE-Int. Soc. Opt. Eng., 5269, pp.183-191 (2004).
“An imaging fiber-based optical tweezer array for microparticle array assembly,” Jenny M. Tam, Israel Biran, and David R. Walt, Appl. Phys. Lett., 84, pp. 4289-4291 (2004).
“Living Bacterial Cell Array for Genotoxin Monitoring,” Yina Kuang, Israel Biran, and David R. Walt, Anal. Chem., 76, pp. 2902-2909 (2004).
“Reversible ratiometric probe for qualitative DNA measurements.” Joern Ueberfeld, and David R. Walt, Anal. Chem., 76, pp. 947-952 (2004).
“Encoded fiber-optic microsphere arrays for probing protein-carbohydrate interaction,” Eddie W. Adams, Joern Ueberfeld, Daniel M. Ratner, Barry R. O’Keefe, David R. Walt, and Peter H. Seeberger, Angew. Chem., Int. Ed., 115, pp. 5475-5478 (2003).
“High-density, microsphere-based fiber optic DNA microarrays,” Jason R. Epstein, Amy P.K. Leung, Kyong-Hoon Lee, and David R. Walt, Biosens, Bioelectron., 18, pp. 541-546 (2003).
“Optical imaging fiber-based live bacterial cell array biosensor,” Israel Biran, David M. Rissin, Eliora Z. Ron, and David R. Walt, Anal. Biochem, 315, pp. 106-113 (2003).
“Combinational Decoding: An Approach for Universal DNA Array Fabrication”, Jason R. Epstein, Jane A. Ferguson, Kyong-Hoon Lee and David R. Walt, J. Am. Chem. Coc, 125, pp. 13753-13759 (2003).
“Spatially Resolved Electrochemiluminescence on an Array of Electrode Tips”, S. Szunerits, J.M. Tam, L. Thouin, C. Amatore, and David R. Walt, Anal. Chem, 75, pp. 4382-4388 (2003).
“Flourescence-based fiber optic arrays: a universal platform for sensing”, Jason R. Epstein and David R. Walt, Chem. Soc. Rev, 32, pp. 203-214 (2003).
“Information Coding in Artificial Olfaction Multisensor Arrays”, Keith J. Albert and David R. Walt, Anal Chem, 75, pp. 4161-4167 (2003).
“The use of optical fiber bundles combined with electrochemistry for chemical imaging”, Sabine Szunerits and David R. Walt, ChemPhysChem, 4, pp. 186-192 (2003).
“Enhancing vapor sensor discrimination by mimicking a canine nasal cavity flow environment”, Shannon E. Stitzel, Deborah R. Stein and David R. Walt, J. Am. Chen. Soc, 125, pp. 3684-3685 (2003).
"Fabrication of Micro- and Nanostructures Using Optical Imaging Fibers and Their Use as Chemical Sensors," Karri L. Michael, Jane A. Ferguson, Brian G. Healey, Sandra L. Schultz, Laura C. Taylor, Paul Pantano, and David R. Walt, Proceedings of the Third International Symposium on Microstructures and Microfabricated Systems, 97-5, pp. 152-158 (1997).
"Simultaneous monitoring of pH, CO2, and O2 using an optical imaging fiber," Jane A. Ferguson, Brian G. Healey, karen S. Bronk, Steven M. Barnard, and David R. Walt, Analytica Chimica Acta, 340, pp. 123-131 (1997).
"In Situ Flourescence Imaging of Localized Corrosion with a pH-Sensitive Imaging Fiber," Anna A. Panova, Paul Pantano, and David R. Walt, Analytical Chemistry, 69, pp. 1635-1641 (1997).
"A fiber-optic DNA biosensor microarray for the analysis of gene expression," Jane A. Ferguson, T. Christian Boles, Christopher P. Adams, and David R. Walt, Nature Biotechnology, 14, pp. 1681-1684 (1996).
"Ordered Nanowell Arrays," Paul Pantano and David R. Walt, Chemistry of Materials, 8, pp. 8832-8835 (1996).
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