What happens when DNA mutates?

Our cultural fascination with mutations has given us X-men and Teenage Mutant Ninja Turtles. In reality, mutations are less likely to lead to superpowers, but they do play important roles in disease and evolution. Our DNA is always under attack by chemicals, radiation, and even our own cellular processes. Luckily we have DNA repair systems to fix most of the damage, but once in a while, mistakes occur in the DNA sequence and are not corrected. Using Next-Generation Sequencing (NGS) we can rapidly sequence DNA and identify these mutations. On a larger scale, the ability to more conveniently locate mutations within a genome is giving us a more detailed understanding of diseases like cancer.

sample collection

Teaching Resources

Classroom Materials

Laboratory Materials

Data Analysis Materials

Next Generation Science Standards
Life Sciences