Recent Publications

2008

Distinct and Long-lived Activity States of Single Enzyme Molecules”,
D.M. Rissin, H.H. Gorris, D.R. Walt, JACS, 2008, (in press)

"Very High Density Sensing Arrays",
Christopher N. LaFratta and David R. Walt, Chem. Rev., 2008 108 (2), 614 - 637 (review)

2007

Fiber-based Single Cell Analysis of Reporter Gene Expression in Yeast Two-hybrid Systems”, R.D. Whitaker, D.R. Walt. Analytical Biochemistry , 2007 360, 63-74

Stochastic Inhibitor Release and Binding from Single-enzyme Molecules”,
H.H. Gorris, D.M. Rissin, D.R. Walt, PNAS, 2007, 104 (45), 17680-17685
            News highlights about this article:
            a) “
Observing Single Enzymes at Work”, Chem. Eng. News, 2007, 85 (44), 8
            b) “
High-throughput, Single-enzyme Assay System”, Anal. Chem., 2008, 80 (1), 5

"Optical-fiber Bundles",
H.H. Gorris, T.M. Blicharz, D.R. Walt, FEBS Journal, 2007, 274 (21), 5462-5470 (review)

"Microsensor Arrays for Saliva Diagnostics ",
T.M. Blicharz, R.B. Hayman, D.M. Rissin, M. Bowden, W.L. Siqueira, E.J. Helmerhorst, N. Grand-Pierre, F.G. Oppenheim, J.S. Bhatia, F.F. Little, J.S. Brody, D.R. Walt, Ann N Y Acad Sci. , 2007 1098, 389-400.

"Smells Like Bread",
D.R. Walt, Nat Chem Biol., 2007 3(6), 325-330

2006

"Fiber Optic Array Biosensors ",
D.R. Walt, Biotechniques , 2006 41(5), 529-535

Microbead Chemical Switches: An Approach to Detection of Reactive Phosphonate Chemical Warfare Agent Vapors”,
S. Bencic-Nagale, T. Sternfeld, D.R. Walt. JACS, 2006 128 (15), 5041-5048

Digital Readout of Target Binding with Attomole Detection Limits via Enzyme Amplification in Femtoliter Arrays, D.M. Rissin, D.R. Walt, JACS, 2006 128 (19), 6286-6287
............News highlight about this article:
............
Single-molecule Binding Assay in Femtoliter Arrays, Anal. Chem., 2006, 78 (13), 4241

Duplexed Sandwich Immunoassays on a Fiber-optic Microarray”,
D.M. Rissin, D.R. Walt. Analytica Chimica Acta, 2006 564 (1), 34-39

Fiber-Optic Microsphere-Based Arrays for Multiplexed Biological Warfare Agent Detection”,
L. Song, S. Ahn, D.R. Walt. Analytical Chemistry, 2006 78 (4),1023-1033

Digital concentration readout of single enzyme molecules using femtoliter arrays and Poisson statistics”,
D.M. Rissin, D.R. Walt. Nano Letters 2006 6 (3), 520-523

2005

Extending the Longevity of Fluorescence-Based Sensor Arrays Using Adaptive Exposure”,
S. Bencic-Nagale, D.R. Walt. Analytical Chemistry, 2005 77, 6155-6162

Simultaneous Detection of Multiple Biological Warfare Agents in Environmental Samples Using Fiber-Optic Microsphere-Based Arrays”,
L. Song, S. Ahn, D.R. Walt. Emerging Infectious Diseases, 2005 11, 1629-1632

Development of a Microfluidic Platform with an Optical Imaging Microarray Capable of Attomolar Target DNA Detection”,
M. Bowden, L. Song, D.R. Walt. Analytical Chemistry, 2005 77 (17), 5583-5588

Fabrication and Optical Characterization of Imaging Fiber Based Nanoarrays”,
J. Tam, L. Song, D.R. Walt. Talanta, 2005 67 (3), 498-502

Monitoring "promiscuous" drug effects on single cells of multiple cell types ”,
Y. Kuang, D.R. Walt. Analytical Biochemistry, 2005 345, 320-325

Optical Fiber-based Sensors: Application to Chemical Biology”,
K.L. Brogan, D.R. Walt, Current Opinion in Chemical Biology, 2005, 9, 494-500.

Advances in Miniature Analytical Methods for Medical Diagnostics”,
D.R. Walt, Science , 2005, 308, 217-219.

Editorial: "Electronic Noses: Wake Up and Smell the Coffee”,
D.R. Walt, Analytical Chemistry A-Pages, 2005, 77 (3), 45A.

Array-based Binary Analysis for Bacterial Typing”,
J. E. Shepard, Y. Danin-Poleg, Y. Kashi, D.R. Walt, Analytical Chemistry, 2005 , 77 , 319-326.

2004

Simultaneously Monitoring Gene Expression Kinetics and Genetic Noise in Single Cells by Optical Well Arrays”,
Y. Kuang, I. Biran, D.R. Walt, Analytical Chemistry, 2004, 76 (21), 6282-6286.

Fabrication of Gold Microtubes and Microwires in High Aspect Ratio Capillary Arrays”,
D. Monk, D.R. Walt, JACS , 2004, 126 (37), 11416-11417.

Optical Fiber-Based Biosensors”,
D. Monk, D.R. Walt, Analytical and Bioanalytical Chemistry, 2004, 379 , 931-945.

Living Bacterial Cell Array for Genotoxin Monitoring”,
Y. Kuang, I. Biran, D.R. Walt, Analytical Chemistry, 2004, 76, 2902-2909.

Reversible Ratiometric Probe for Quantitative DNA Measurements”,
D.R. Walt and J. Ueberfeld, Analytical Chemistry, 2004, 76 (4), 947-952.

2003

Combinatorial Decoding: An Approach for Universal DNA Array Fabrication”,
J. Epstein, J. Ferguson, K. Lee, D.R. Walt, JACS , 2003, 125 , 13753-13759.

The Use of Optical Fiber Bundles Combined with Electrochemistry and Chemical Imaging”,
S. Szunerits and D.R. Walt, Chemphyschem , 2003 (4), 186-192.

Spatially resolved electrochemiluminescence on an array of electrode tips”,
S. Szunerits, J. Tam, L. Thouin, C. Amatore, and D.R. Walt, Anal. Chem ., 2003, 75 , 4382-4388.

Optical Imaging Fiber Based Live Bacterial Cell Array Biosensor”,
I. Biran, D. M. Rissin, E.Z. Ron, and D.R. Walt, Anal. Biochem., 2003, 315 (1), 106-113.

Fluorescence-based Fibre Optic Arrays: A Universal Platform for Sensing”,
D.R. Walt and J. Epstein, Chem. Soc. Reviews, 2003, (32), 203-214.

Encoded Fiber Optic Microsphere Arrays for Probing Protein-Carbohydrate Interactions”,
E. Adams, J. Ueberfeld, D. Ratner, B. O'Keefe, D.R. Walt, P. Seeberger, Angewandte Chemie , 2003 (115), 5475-5478.

 

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