• "Mimicking the Prehairpin Intermediate of gp41: A Screening Platform for Fusion Inhibitors Based on
    Coiled Coil Lipopeptides Assembled in Artificial Biomembranes"
    Steffen Schuy, Nicholas Yoder, Stephan Hobe, Krishna Kumar, Reiner Vogel and Andreas Janshoff*
    Angew. Chem., Int. Ed. 2009, 48, 751-754.
    [Full Text-DOI: 10.1002/anie.200803080]

  • "Fluorinated Lipid Constructs Permit Facile Passage of Molecular Cargo into Living Cells"
    Laila Dafik, Venkateshwarlu Kalsani, Anthony Kar Lun Leung and Krishna Kumar*
    J. Am. Chem. Soc. 2009, 131, 12091-12093.
    [Full Text-DOI: 10.1021/ja902777d]

  • "Protein Design Using Non-Canonical Amino Acids"
    Deniz Yüksel, Diren Pamuk, Yulia Ivanova and Krishna Kumar*
    in Protein Engineering and Design Park, S.; Cochran, J. Eds.,
    Taylor & Francis 2009, pp. 205-222.
    [Full Text-ISBN: 1420076582]

  • "Biosynthesis of Stable Coiled-Coils Containing (2S,4R)-5,5,5-Trifluoroleucine and
    (2S,4S)-5,5,5-Trifluoroleucine"
    Jin Kim Montclare, Soojin Son, Ginevra Clark, Krishna Kumar and David Tirrell*
    ChemBioChem 2009, 10, 84-86.
    [Full Text-DOI: 10.1002/cbic.200800164]

  • "A New Paradigm for Design of Protein and Biomolecular Assemblies"
    Gizem Akçay and Krishna Kumar*
    J. Fluorine Chem. 2009, 130, 1178-1182.
    [Full Text-DOI: 10.1016/j.jfluchem.2009.09.002]

  • "Lipopeptides Derived from HIV and SIV Mimicking the Prehairpin Intermediate
    of gp41 on Solid Supported Lipid Bilayers"
    Steffen Schuy, Edith Schäfer, Nicholas C. Yoder, Krishna Kumar, Reiner Vogel and Andreas Janshoff*
    J. Struct. Biol. 2009, 168, 125-136.
    [Full Text-DOI: 10.1016/j.jsb.2009.04.006]

  • "Fluorinated Amino Acids and Biomolecules in Protein Design and Chemical Biology"
    He Meng, Ginevra Clark and Krishna Kumar*
    in Fluorine in Medicinal Chemistry and Chemical Biology Ojima, I. and Taguchi, T. Eds.,
    John Wiley & Sons 2009, pp. 411-446.
    [Full Text-ISBN: 1405167203]

  • "Influence of Selective Fluorination on the Biological Activity and Proteolytic
    Stability of Glucagon-like Peptide-1"
    He Meng, Subrahmanian T Krishnaji, Martin Beinborn and Krishna Kumar*
    J. Med. Chem. 2008, 51, 7303-7307.
    [Full Text-DOI: 10.1021/jm8008579]

    See also:
    "Fluorous Peptides Get Ready to Heal" by Stephen Ritter*
    C&EN 2007, 85 (37), pp. 36-37.
    [Full Text-HTML, PDF]

  • "Fluorination of Mammalian Cell Surfaces via the Sialic Acid Biosynthetic Pathway"
    Laila Dafik, Marc d'Alarcao,* and Krishna Kumar*
    Bioorg. Med. Chem. Lett. 2008, 18, 5945-5947.
    [Full Text-DOI: 10.1016/j.bmcl.2008.09.010]

  • "Structure and Thermotropic Phase Behavior of Fluorinated Phospholipid Bilayers: A
    Combined Attenuated Total Reflection FTIR Spectroscopy and Imaging Ellipsometry Study"
    Steffen Schuy, Simon Faiss, Nicholas Yoder, Venkateshwarlu Kalsani,
    Krishna Kumar,* Andreas Janshoff,* and Reiner Vogel*
    J. Phys. Chem. B 2008, 112, 8250-8256.
    [Full Text-DOI: 10.1021/jp800711j]

  • "Peptide Tertiary Structure Nucleation by Sidechain Crosslinking with Metal Complexation and
    Double "Click" Cycloaddition"
    Oscar Torres, Deniz Yüksel, Matt Bernardina, Krishna Kumar and Dennis Bong*
    ChemBioChem 2008, 9, 1701-1705.
    [Full Text-DOI: 10.1002/cbic.200800040]

  • "Engineering and Characterization of a Single Chain Surrogate Light Chain Variable Domain"
    Lucia Morstadt, Andrew Bohm, Deniz Yüksel, Krishna Kumar, David B. Stollar and James D. Baleja*
    Protein Sci. 2008, 17, 458-465.
    [Full Text: HTML, PDF]

  • "Antimicrobial Activity and Protease Stability of Peptides Containing Fluorinated Amino Acids"
    He Meng and Krishna Kumar*
    J. Am. Chem. Soc. 2007, 129, 15615-15622.
    [Full Text-DOI: 10.1021/ja075373f]

    See also:
    "Fluorous Peptides Get Ready to Heal" by Stephen Ritter*
    C&EN 2007, 85 (37), pp. 36-37.
    [Full Text-HTML, PDF]

    "Putting the "F" in peptides" by Randall C Willis*
    Drug Discovery News 2007, December.
    [Full Text-HTML]

  • "Nanoscale Patterning in Mixed Fluorocarbon-Hydrocarbon Phospholipid Bilayers"
    Nicholas Yoder, Venkateshwarlu Kalsani, Steffen Schuy, Reiner Vogel, Andreas Janshoff* and Krishna Kumar*
    J. Am. Chem. Soc. 2007, 129, 9037-9043.
    [Full Text-DOI: 10.1021/ja070950l]

  • "The Role of Dimer Interface Histidine in the pH-Dependent Stability of
    Human Papillomavirus Type 16 E2 Protein"
    Kakoli Bose, Nicholas C. Yoder, Krishna Kumar and James D. Baleja*
    Biochemistry 2007, 46, 1402-1411.
    [Full Text-DOI: 10.1021/bi0611255]

  • "Fluorinated Amino Acids and Reagents in Protein Design and Biomolecule Separation"
    He Meng, Venkateshwarlu Kalsani and Krishna Kumar*
    ACS Symposium Series 2007, 949, 487-499.
    Current Fluoroorganic Chemistry. New Synthetic Directions, Technologies,
    Materials and Biological Applications. Soloshonok, V. A.; Mikami, K.; Yamazaki, T.;
    Welch, J. T., and Honek, J. Eds., Oxford University Press/ACS

  • "Bioorthogonal Noncovalent Chemistry: Fluorous Phases in Chemical Biology"
    Nicholas Yoder, Deniz Yüksel, Laila Dafik and Krishna Kumar*
    Curr. Opin. Chem. Biol. 2006, 10, 576-583.
    [Full Text-DOI: 10.1016/j.cbpa.2006.10.007]

  • "Fluorinated Interfaces Drive Self Association of Transmembrane Helices in Lipid Bilayers"
    Natascha Naarmann, Basar Bilgiçer, He Meng, Krishna Kumar* and Claudia Steinem*
    Angew. Chem., Int. Ed. 2006, 45, 2588-2591.
    [Full Text-DOI: 10.1002/anie.200503567]

  • "A Fluorous Capping Strategy for Fmoc-based Automated and Manual
    Solid Phase Peptide Synthesis"
    Vittorio Montanari and Krishna Kumar*
    Eur. J. Org. Chem. 2006, 874-877.
    [Full Text-DOI: 10.1002/ejoc.200500958]

  • "Selective Protein-Protein Interactions Driven by a Phenylalanine Interface"
    Nicholas C. Yoder and Krishna Kumar*
    J. Am. Chem. Soc. 2006, 128, 188-191.
    [Full Text-DOI: 10.1021/ja055494k]

  • "Enabling Routine Fluorous Capping in Solid Phase Peptide Synthesis"
    Vittorio Montanari and Krishna Kumar*
    J. Fluorine Chem. 2006, 127, 565-570.
    [Full Text-DOI: 10.1016/j.jfluchem.2005.12.028]

  • "Controlling Association of Vesicle Embedded Peptides by Alteration of the Physical
    State of the Lipid Matrix"
    Natascha Naarmann, Basar Bilgiçer, Krishna Kumar* and Claudia Steinem*
    Biochemistry 2005, 44, 5188-5195.
    [Full Text-DOI: 10.1021/bi050096f]

    See also: Biochemistry 2005, 44, 10750.
    [Full Text-DOI: 10.1021/bi058018f]

  • "De Novo Design of Defined Helical Bundles in Membrane Environments"
    Basar Bilgiçer and Krishna Kumar*
    Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 15324-15329.
    [Full Text-DOI: 10.1073/pnas.0403314101]

    Also featured on the cover of PNAS

  • "Alternative Translations of a Single RNA Message: An Identity Switch of
    (2S,3R)-4,4,4-Trifluorovaline between Valine and Isoleucine Codons"
    Pin Wang, Alfio Fichera, Krishna Kumar and David Tirrell*
    Angew. Chem., Int. Ed. 2004, 43, 3664-3666.
    [Full Text-DOI: 10.1002/anie.200454036]

    Also featured as a Communications Frontispiece

  • "Just Add Water: A New Fluorous Capping Reagent for Facile Purification
    of Peptides Synthesized on the Solid Phase"
    Vittorio Montanari and Krishna Kumar*
    J. Am. Chem. Soc. 2004, 126, 9528-9529.
    [Full Text-DOI: 10.1021/ja0479033]

  • "A Highly Stereospecific and Efficient Synthesis of Homopentafluorophenylalanine"
    I. Ramesh Babu, Edward K. Hamill and Krishna Kumar*
    J. Org. Chem. 2004, 69, 5468-5470.
    [Full Text-DOI: 10.1021/jo049206z]

  • "Protein Design Using Unnatural Amino Acids"
    Basar Bilgiçer and Krishna Kumar*
    J. Chem. Ed. 2003, 80, 1275.
    [Full Text-HTML]

  • "Fluorinated Amino Acids in Protein Design and Engineering"
    Nicholas Yoder and Krishna Kumar*
    Chem. Soc. Rev. 2002, 31, 335-341.
    [Full Text-DOI: 10.1039/b201097f ]

    See also: Hot Articles - Royal Society of Chemistry
    Also featured in: Chemical Biology Virtual Journal - Royal Society of Chemistry

  • "A Simple and Efficient Method for the Resolution of All Four
    Diastereomers of 4,4,4-Trifluorovaline and 5,5,5-Trifluoroleucine"
    Xuechao Xing, Alfio Fichera and Krishna Kumar*
    J. Org. Chem. 2002, 67, 1722-1725.
    [Full Text-DOI: 10.1021/jo011097q]

    See also: J. Org. Chem. 2002, 67, 8290.
    [Full Text-DOI: 10.1021/jo027968t]

  • "Synthesis and Thermodynamic Characterization of Self-Sorting Coiled Coils"
    Basar Bilgiçer and Krishna Kumar*
    Tetrahedron 2002, 58, 4105-4112.
    [Full Text-DOI: 10.1016/S0040-4020(02)00260-0]

  • "Programmed Self-Sorting of Coiled Coils with
    Leucine and Hexafluoroleucine Cores"
    Basar Bilgiçer, Xuechao Xing and Krishna Kumar*
    J. Am. Chem. Soc. 2001, 123, 11815-11816.
    [Full Text-DOI: 10.1021/ja016767o]

    See also: Science & Technology Roundup
    C&EN 2001, 79 (49), p. 35.
    [Full Text-HTML, PDF]

  • "A Coiled Coil with a Fluorous Core"
    Basar Bilgiçer, Alfio Fichera and Krishna Kumar*
    J. Am. Chem. Soc. 2001, 123, 4393-4399.
    [Full Text-DOI: 10.1021/ja002961j]

    See also:
    "Fluorous Peptides" by Stu Borman*
    C&EN 2001, 79 (20), pp. 41-42.
    [Full Text-HTML, PDF]

    Heart Cut
    Chemical Innovation 2001, 31 (11), p. 10.
    [Full Text-HTML, PDF]

    "Steps Towards Nanotechnology" by Jeffrey Soreff*
    Institute for Molecular Manufacturing (IMM)
    IMM Report No. 26, October 23, 2001.
    [Full Text-HTML, PDF]

  • "A Novel Synthesis of Enantiomerically Pure 5,5,5,5',5',5'-Hexafluoroleucine"
    Xuechao Xing, Alfio Fichera and Krishna Kumar*
    Org. Lett. 2001, 3, 1285-1286.
    [Full Text- DOI: 10.1021/ol015567e]

  • "Fluorophobic Acceleration of Diels-Alder Reactions"
    Kathleen E. Myers and Krishna Kumar*
    J. Am. Chem. Soc. 2000, 122, 12025-26.
    [Full Text-DOI: 10.1021/ja0019777]


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