implantable tech

RESEARCH                             PEOPLE                             PUBLICATIONS                           NEWS & MEDIA                            TECHNOLOGY TRANSFER



 

We are revisiting biopolymers in a high-tech context. Specifically, silk fibroin extracted from silkworm cocoons is a unique biopolymer that combines biocompatibility, implantability, along with excellent optical properties. We study the use of silk as an optical material for applications in biomedical engineering, photonics and nanophotonics.

Silk can be nanopatterned with features smaller than 20 nm. This allows manufacturing of structures  such as (among others) holographic gratings, phase masks, beam diffusers and photonic crystals out of a pure protein film. The properties of silk allow these devices to be "biologically activated" offering new opportunities for sensing and biophotonic components. 


RELEVANT PUBLICATIONS


Bioactive silk protein biomaterial systems for optical devices. Biomacromolecules, 2008. 9(4): p. 1214-1220.

A new route for silk. Nature Photonics, 2008. 2(11): p. 641-643

Biocompatible Silk Printed Optical Waveguides. Advanced Materials, 2009. 21(23): p. 2411

Implantable, multifunctional, bioresorbable optics. Proceedings of the National Academy of Sciences of the United States of America, 2012. 109(48): p. 19584-19589

Synthesis and characterization of biocompatible nanodiamond-silk hybrid material. Biomedical Optics Express, 2014. 5(2): p. 596-608.

A Physically Transient Form of Silicon Electronics, Science, 337 (2012) 1640-1644

Fabrication of Silk Microneedles for Controlled-Release Drug Delivery, Adv. Funct. Mater., 22 (2012) 330-335

Materials for Bioresorbable Radio Frequency Electronics. Advanced Materials, 2013. 25(26): p. 3526-3531

Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection abatement. Proceedings of the National Academy of Sciences of the United States of America, 2014. 111(49): p. 17385-17389

Laser-based three-dimensional multiscale micropatterning of biocompatible hydrogels for customized tissue engineering scaffolds. Proceedings of the National Academy of Sciences of the United States of America, 2015. 112(39): p. 12052-12057

Reflective chemotherapy

implantable light sources