Abstracts & Peer Reviewed Manuscripts

Abstracts and Conference Presentations:

1. Georgakoudi I, Levitt J^g, Baldwin A, Papadakis A, Munger K. Intrinsic fluorescence changes associated with apoptosis of human epithelial keratinocytes. 4^th International Conference on Cervical Cancer, Houston, TX, May 2005. Gynecologic Oncology 2005; 99:854-857.
2. Mujat C, Papadakis A, Tian F, Munger C, Georgakoudi I. Characterization of human epithelial keratinocytes with angular light scattering spectroscopy. Engineering Conferences International: Advances In Optics For Biotechnology, Medicine And Surgery, Copper Mountain, Colorado,  July 24-28, 2005.
3. Levitt J^g, Baldwin A, Munger K, Georgakoudi I. Instrinsic Fluorescence Changes Associated With Cisplatin-induced Apoptosis of Human Epithelial Keratinocytes. Engineering Conferences International: Advances In Optics For Biotechnology, Medicine And Surgery, Copper Mountain, Colorado,  July 24-28, 2005.
4. Angheloiu GO, Georgakoudi I, Haka AS, Arendt JT, Mueller MG, Motz JT, Dasari RR, Fitzmaurice M, Kramer JR, Feld MS. Detection of coronary plaques with superficial foam cells using intrinsic fluorescence at 308 and 480 nm excitation wavelengths. J Am Coll Cardiol. 2005;45:45A.
5. Georgakoudi I, Solban N, Rice W^g, Lin C, Hasan T. In vivo flow cytometry: A noninvasive method for monitoring circulating cells after PDT. Presented at the Annual Optics East Meeting of the International Society for Optical Engineering. Boston, MA, 23-26 October, 2005.
6. Mujat C, Papadakis A, Tian F, Munger K, Georgakoudi I. Light scattering spectroscopy investigation of human epithelial keratinocytes. 26^th Annual meeting of the American Society of Lasers in Medicine and Surgery, Boston, MA, April 5-9, 2006. Lasers Surg Med 2006: 16-16 45 Suppl.18.
7. Levitt J^g, Xylas J^u, Baldwin A, Münger K, Georgakoudi I. Instrinsic fluorescence changes associated with cisplatin-induced apoptosis of human epithelial keratinocytes. 26^th Annual meeting of the American Society of Lasers in Medicine and Surgery, Boston, MA, April 5-9, 2006.
8. Georgakoudi I, Tsai I, Kaplan D. Optical Spectroscopy and Imaging as a Tool for Characterizing Silk as a Novel Biomaterial for Tissue Engineering Applications. Biomedical Topical Meeting of the Optical Society of America, Ft. Lauderdale, FL, Mar19-23, 2006. Technical Digest.
9. Greiner C^g, Stucenski L^g, Boutrus S^g, Levitt J^g, Georgakoudi I. Tryptophan autofluorescence imaging of epithelial cells. 26^th Annual meeting of the American Society of Lasers in Medicine and Surgery, Boston, MA, April 5-9, 2006. Lasers Surg Med 2006; 86-86 289 Suppl. 18.
10. Boutrus S^g, Greiner C^g, Georgakoudi I. Real time detection of circulating cancer cells in a mouse model by a portable in vivo flow cytometer. 26^th Annual meeting of the American Society of Lasers in Medicine and Surgery, Boston, MA, April 5-9, 2006. Lasers Surg Med 2006; 83-83 281 Suppl. 18.
11. Georgakoudi I, Levitt J^g, Mujat C, Greiner C^g, Stucenski L^g, Munger K. Development of Novel Biomarkers Based on Optical Tissue Spectroscopy and Imaging of Endogenous Signals. Presented at SPIE Photonics North meeting, Quebec City, Canada, June 2006
12. J. Levitt^g, M. McLaughlin-Drubin, J. Garlick, K. Münger, I. Georgakoudi. Non-Invasive Assessment of Cell Differentiation in 3-D Tissue Models by Intrinsic Fluorescence Measurements. Gordon Research Conference: Lasers in Medicine and Biology, July 2-7, 2006.
13. Greiner C^g, L Stucenski^g,  et al.,  Tryptophan, NADH and FAD autofluorescence imaging of normal, pre-cancerous and cancerous epithelial cells. Gordon Research Conference: Lasers in Medicine and Biology, July 2-7, 2006.
14. W. Rice^g, S. Firdous , J. Mauney, V. Volloch, D. Kaplan and I. Georgakoudi. Optical, non-invasive monitoring of stem cell differentiation into adipogenic and osteogenic pathways. Gordon Research Conference: Lasers in Medicine and Biology, July 2-7, 2006
15. Boutrus S^g, C. Greiner^g, I. Georgakoudi, "Real-time monitoring of multiple blood cell populations by a portable two Color in vivo flow cytometer", presented at GRC: Lasers in Medicine and Biology, July 2-7, 2006 – poster presentation
16. Georgakoudi I, Firdous S, Rice W^g, Tsai I, Kaplan D. Optical imaging and spectroscopy for non-invasive characterization of biomaterials in tissue engineering. 1^st Annual conference on Methods in Bioengineering, Boston MA, July 17-21 2006.
17. Georgakoudi I, Levitt J^g, Baldwin A, Mujat C, Greiner C^g, Stucenski L^g, Munger K. Linear and non-linear optical microscopy and spectroscopy of human papilloma virus transfected cells. SPIE Optics East conference, Boston MA, September 2006.
18. Georgakoudi I, Rice W^g, Firdous S, Mauney J, Volloch V, Kaplan D. Imaging of intrinsic optical stem cell changes in engineered tissues. Presented at the Annual meeting of the Optical Society of America, Rochester NY, October 2006.
19. J. Xylas^u, J. Levitt^g<, C. Egles, J. Garlick, I. Georgakoudi. Multi-photon imaging of endogenous chromophores in engineered normal and (pre-) cancerous tissues. Biomedical Engineering Society Annual Fall Meeting Friday, Oct 13 2006 Chicago, Illinois.
20. W. Rice^g, C. Bayan^g, S. Firdous ,  J. Mauney, V. Volloch, D. Kaplan and I. Georgakoudi. Optical, non-invasive monitoring of stem cell differentiation into adipogenic and osteogenic pathways. SPIE Photonics West, San Jose CA, January 20-25, 2007
21. Georgakoudi I, Canizzarro C, Lovett M^g, Vunjak-Novakovic G, Kaplan D. Progress in Imaging Methods Related to Tissue Engineering. SPIE Photonics West, San Jose CA, January 20-25, 2007.
22. Georgakoudi I, Rice W^g, Firdous S, Kim HJ, Preda C, Wang W, Kaplan D. Characterization of the non-linear optical properties of silk as a novel biomaterial for tissue engineering. SPIE Photonics West, San Jose CA, January 20-25, 2007.
23. Georgakoudi I, Rice W^g, Tsai I, Firdous S, Gupta S, Kaplan D. Characterization of linear and non-linear optical properties of biomaterials in engineered tissues. 16^th International Conference on Dynamical Processes in Excited States of Solids. Segovia Spain, June 17-21, 2007. Accepted
24. Greiner C^g, Mujat C, Baldwin A, Levitt J^g, Munger K and Georgakoudi I. Autofluorescence and light scattering signatures of normal and human papillomavirus immortalized human foreskin keratinocytes. Engineering Conferences International: Advances In Optics For Biotechnology, Medicine And Surgery, Naples FL,  June 11-14, 2007.
25. Levitt J^g, McLaughlin-Drubin M, Xylas J^u, Garlick J, Munger K, Georgakoudi I. Quantitative characterization of biochemical and morphological changes of engineered normal, dysplastic and cancerous tissues. Engineering Conferences International: Advances In Optics For Biotechnology, Medicine And Surgery, Naples FL,  June 11-14, 2007.

1. Georgakoudi I, Solban N, Novak J, Rice W, Hasan T, Lin C. In vivo flow cytometry: A new method for enumerating circulating tumor cells. Cancer Res 2004; 64: 5044-5047.
2. Wei X, Sipkins D, Pitsillides C, Novak J, Georgakoudi I, Lin C. Real-time detection of circulating apoptotic cells by in vivo flow cytometry. Mol Imaging 2005; 4: 415-416.
3. Georgakoudi IVan Dam JCharacterization of Dysplastic Tissue Morphology and Biochemistry in Barrett’s Esophagus using Diffuse Reflectance and Light Scattering Spectroscopy. Techniques in Gastrointestinal Endoscopy 2005;7:100-105.
4. Georgakoudi I. The Color of Cancer. J. Luminescence 2006;119-120: 75-83.
5. Angheloiu G, Arendt, J, Müller, M, Haka, A, Georgakoudi I, Motz J, Scepanovic O, Kuban B, Myles J, Miller F, Podrez E, Fitzmaurice M, Kramer J, Feld M. Intrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion. Arteriosclerosis, Thrombosis, and Vascular Biology 2006; 26:1594-600.
6. Levitt J^g, Baldwin A, Papadakis A, Puri S^u, Xylas J^u, Munger K, Georgakoudi I. Intrinsic fluorescence and redox changes associated with apoptosis of primary epithelial cells. Journal of Biomedical Optics 2006;11:064012 (Cover feature).
7. Georgakoudi I, Tsai I, Greiner C^g, Wong C^g, DeFelice J^g, Kaplan D. Intrinsic fluorescence changes associated with the structural conformation of silk fibroin in biomaterial matrices. Optics Express 2007;15: 1043-1053.
8. Boutrus S^u, Greiner C^g, Hwu D^u, Chan M, Kuperwasser C, Lin C, Georgakoudi I. A Portable Two-Color In Vivo Flow Cytometer for Real-Time Detection of Fluorescently-Labeled Circulating Cells. JBO Letters 2007; In Press.
9. Perry H^u, Greiner C^g, Georgakoudi I, Cronin-Golomb M, Omenetto F. Simple fabrication technique for rapid prototyping of seamless cylindrical microchannels in polymer substrates. Review of Scientific Instruments 2007; In Press.
10. Kim HJ, Kim U.J, Leisk G, Bayan C^g, Georgakoudi I, Kaplan DL. Bone regeneration on macroporous aqueous-derived silk 3-D scaffolds. Macromolecular Bioscience 2007; In Press.
11. Rice WL, Kaplan DL, Georgakoudi I. Quantitative biomarkers of stem cell differentiation based on intrinsic two-photon excited fluorescence. J Biomed Opt. 2007 Nov-Dec;12(6):060504.
12. Rice WL, Firdous S, Gupta S, Hunter M, Foo CW, Wang Y, Kim HJ, Kaplan DL, Georgakoudi I. Non-invasive characterization of structure and morphology of silk fibroin biomaterials using non-linear microscopy. Biomaterials. 2008 Feb 19