About the Group
The ODDET group at the Tufts BME department focuses on the development of
optical spectroscopic imaging approaches to monitor and characterize biochemical
and morphological aspects of tissue in non-invasive ways. The work relies heavily
on optical instrument development and quantitative data analysis approaches that
often involve modeling and understanding of the detailed interactions between
light and biological matter. Our approaches exploit linear and non-linear optical
phenomena and include light scattering spectroscopy, linear and non-linear microscopy
(second harmonic generation and two-photon excited fluorescence) and flow cytometry.
Specific applications of our work include early cancer detection and monitoring of
tissue development in engineered tissues. These projects are pursued with collaborators
at Tufts, the Massachusetts General Hospital and the Brigham & Women's Hospital.
The group consists of undergrads, graduate students, postdoctoral fellows and
senior research scientists.