Publications

Book Chapters:

Mirkin S. (2006) “Replication of Expandable Repeats”. In: Genetic Instabilities and Neurological Diseases, 2nd ed., R.D. Wells and T. Ashizawa eds., pp. 637-644. [PDF]

Krasilnikova, M.M., Mirkin, S.M. (2004) Analysis of triplet repeat replication by 2-dimensional gel-electrophoresis. In: Methods in Molecular Biology, vol. 277: Trinucleotide Repeat Protocols. Edited by: Y. Kohwi © Humana Press Inc., Totowa, NJ, pp.19-28. [PDF]

Mirkin, S.M. (2001) DNA topology: Fundamentals. In: Encylopedia of Life Sciences, London: Nature Publishing Group. [PDF]

Mirkin, S.M. (1999) Structure and biology of H DNA. In: Triple Helix Forming Oligonucleotides, Kluwer Academic Publishers (Norwell, MA) C. Malvy and A. Harel-Bellan eds., pp. 193-222. [PDF]

Articles:

Mirkin S.M. (2008) Discovery of alternative DNA structures: a heroic decade (1979-1989). Front Biosci 13, 1064-1071. [PDF]

Mirkin S.M. (2007) Expandable DNA repeats and human disease. Nature 447, 932-940. [PDF]

Mirkin, E.V., Mirkin, S.M. (2007) Replication fork stalling and natural impediments. Microbiol Mol Biol Rev. 71, 13-35. [PDF]

Krasilnikova, M.M., Kireeva, M.L., Petrovic, V., Knijnikova, N., Kashlev, M., Mirkin, S.M. (2007) Effects of Friedreich’s ataxia (GAA)n.(TTC)n repeats on RNA synthesis and stability. Nucleic Acids Res. 35, 1075-1084. [PDF]

Mirkin, S.M. (2006) DNA structures, repeat expansions and human hereditary disorders. Curr. Opin. Struct. Biol. 16, 1-8. [PDF]

Mirkin, E. V., Castro Roa D., Nudler E., Mirkin, S.M. (2006) Transcription regulatory elements are punctuation marks for DNA replication. Proc. Natl. Acad. Sci. USA 103, 7276-7281. [PDF]

Mirkin, S.M. (2005) Toward a unified theory for repeat expansions. Nature Struct. Mol. Biol. 12, 635-637. [PDF]

Mirkin, E. V., Mirkin, S.M. (2005) Mechanisms of transcription-replication collisions in bacteria. Mol. Cell. Biol. 25, 888-895. [PDF]

Krasilnikova, M.M., Mirkin, S.M. (2004) Replication stalling at Friedreich’s ataxia (GAA)n repeats in vivo. Mol. Cell. Biol. 24, 2286-2295. [PDF]

Mirkin, S.M. (2004) Molecular models for repeat expansions. Chemtracts - Biochem. Mol. Biol.17, 639-662. [PDF]

Bondar, T., Mirkin, E.V., Ucker, D.S., Walden, W.E., Mirkin, S.M., Raychaudhuri, P. (2003) S. pombe Ddb1 is functionally linked to the replication checkpoint pathway. J. Biol. Chem. 278, 37006-37014. [PDF]

Pelletier, R., Krasilnikova, M.M., Samadashwily, G.M., Lahue, R., Mirkin. SM. (2003) Replication and expansion of trinucleotide repeats in yeast. Mol. Cell. Biol., 23, 1349-1357. [PDF]

Mirkin, S.M., Smirnova, E.V. (2002) Positioned to expand. Nature Genet., 31, 5-6. [PDF]

Mirkin, S.M. (2002) Thinking of R. B. Khesin. Mol. Biol. (Mosk.) 36, 347-360. [PDF]
[PDF in Russian]

Siyanova, E. Y., Mirkin, S.M. (2001) Expansion of trinucleotide repeats. Mol. Biol (Mosk.) 35, 168-182. [PDF]  [PDF in Russian]

Krasilnikova, M.M., Smirnova, E.V., Krasilnikov, A.S., Mirkin, S.M. (2001) A new trick for an old dog: TraY binding to a homopurine-homopyrimidine run attenuates replication. J. Mol. Biol. 313, 271-282. [PDF]

Raca, G, Siyanova, E.Y., McMurray, C.T., Mirkin, S.M. (2000) Expansion of the (CTG)n repeat in the 5'-UTR of a reporter gene impedes translation. Nucleic Acids Res. 28, 3943-3949. [PDF]

Krasilnikova, M.M., Samadashwily, G.M., Mirkin, S.M. (1999) Replication of simple DNA repeats. Gene Ther. Mol. Biol. 3, 397-412.

Krasilnikov, A.S., Podtelezhnikov, A., Vologodskii, A., Mirkin, S.M. (1999) Large-scale effects of transcriptional DNA supercoiling in vivo. J Mol. Biol. 292, 1149-1160. [PDF]

Krasilnikova, M.M., Samadashwily, G.M., Krasilnikov, A.S., Mirkin. S.M. (1998) Transcription through a simple DNA repeat blocks replication elongation. EMBO J., 17, 5095-5102. [PDF]

Samadashwily, G.M., Raca, G., Mirkin, S.M. (1997) Trinucleotide repeats affect DNA replication in vivo. Nature Genet., 17, 298-304. [PDF]

Mirkin, S.M. (1997) Everything you always wanted to know about triplexes (but were afraid to ask). J. Am. Chem. Soc. 119, 6692.

Cox, R., Mirkin, S.M. (1997) Characteristic enrichment of DNA repeats in different genomes. Proc. Natl. Acad. Sci. USA 94, 5237-5242. [PDF]

Krasilnikov, A.S., Panyutin, I.G., Samadashwily, G.M., Cox, R., Lazurkin, Yu.S., Mirkin, S.M. (1997) Mechanisms of triplex-caused polymerization arrest. Nucleic Acids Res. 25, 1339-1346. [PDF]

Frank-Kamenetskii, M.D., Mirkin, S.M. (1995) Triplex DNA structures. Annu. Rev. Biochem. 64, 65-95. [PDF]

Samadashwily, G.M., Mirkin, S.M. (1994) Trapping DNA polymerases using triplex-forming oligodeoxyribonucleotides. Gene 149, 127-136. [PDF]

Raghu G., Tevosian, S., Anant, S., Subramanian, K.N., George, D.L, Mirkin, S.M. (1994) Transcriptional activity of the homopurine-homopyrimidine repeat of the c-Ki-ras promoter is independent of its H-forming potential. Nucleic Acids Res. 22, 3271-3279. [PDF]

Mirkin, S.M., Frank-Kamenetskii, M.D. (1994) H-DNA and related structures. Annu. Rev. Biophys. Biomol. Struct. 23, 541-576. [PDF]

Samadashwily, G.M., Dayn, A., Mirkin, S.M. (1993) Suicidal nucleotide sequences for DNA polymerization. EMBO J. 12, 4975-4983. [PDF]

Dayn, A., Samadashwily, G.M., Mirkin, S.M. (1992) Intramolecular DNA triplexes: Novel sequence requirements and influence on DNA polymerization. Proc. Natl. Acad Sci. USA 89, 11406-11410. [PDF]

Dayn, A., Malkhosyan, S., Mirkin, S.M. (1992) Transcriptionally driven cruciform formation in vivo. Nucleic Acids Res. 20, 5991-5997. [PDF]

Pestov, D.G., Dayn, A., Siyanova, E.Yu., George, D.L., Mirkin, S.M. (1991) H-DNA and Z-DNA in the mouse c-Ki-ras promoter. Nucleic Acids Res. 19, 6527-6532. [PDF]

Dayn, A., Malkhosyan, S.R., Duzhii, D.I., Lyamichev, V.I., Panchenko, Y.A., Mirkin, S.M. (1991) Formation of (dA-dT)n cruciforms in Escherichia coli cells under different environmental conditions. J. Bacteriol. 173, 2658-2664. [PDF]

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