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Publications

Reviews and Hypotheses

Fields, C., and Levin, M., (2017), Multiscale Memory And Bioelectric Error Correction In The Cytoplasm-Cytoskeleton-Membrane System, WIREs Systems Biology and Medicine, in press

Monsoro-Burq, A.H., and Levin, M., (2017), How the Chicken and the Egg Taught us to Tell Right From Left: Contribution of Avian Models to the Study of Invariant Asymmetry in Embryogenesis, International Journal of Developmental Biology, in press

McLaughlin, K. A., Levin, M., (2017), Bioelectric Signaling in Regeneration: Mechanisms of Ionic Controls of Growth and Form, Developmental Biology, in press

Martyniuk, C., and Levin, M., (2017), The Bioelectric Code: An Ancient Computational Medium for Dynamic Control of Growth and Form, BioSystems, in press

Adams, D. S., Tseng. A-S., and Levin, M., (2017), Using optogenetics in vivo to stimulate regeneration, in "Optogenetics: from neuronal function to Mapping and Disease Biology", edited by Krishnarao Appasani, Cambridge University Press

Mathews, J., and Levin, M., (2017), Gap Junctional Signaling in Pattern Regulation: physiological network connectivity instructs growth and form, Developmental Neurobiology, 77(5): 643-673
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Levin, M., Pezzulo, G., and Finkelstein, J. M., (2017), Endogenous Bioelectric Signaling Networks: Exploiting Voltage Gradients for Control of Growth and Form, Annual Review of Biomedical Engineering, vol. 19, in press
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Blackiston, D. J., and Levin, M., (2017), Reversals of Bodies, Brains, and Behavior: quantitative analysis of laterality and its disturbance in model species, in "Lateralized Brain Functions", edited by Dr. Wolfgang Walz, Neuromethods 122: 668-695
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Levin, M., and Adams, D. S., (2016), Ahead of the Curve: hidden breakthroughs in the biosciences, Vol. 1, IOP Publishing Ltd

Levin, M., Klar, A. J. S., Ramsdell, A., (2016), Introduction to provocative questions in Left-Right asymmetry, Philosophical Transactions B, 371: 20150399
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McDowell, G., Rajadurai, S., and Levin, M., (2016), From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning, Philosophical Transactions B, 371: 20150409
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Tuszynski, J., Tilli, T. M., Levin, M., (2016), Ion channel and neurotransmitter modulators as electroceutical approaches to the control of cancer, Current Pharmaceutical Design, in press

Pezzulo, G., and Levin, M., (2016), Top-down Models in biology: Explanation and control of complex living systems above the molecular level, Journal of the Royal Society Interface, 13: 20160555
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Herrera-Rincon, C., Guay, J., and Levin, M., (2016), Bioelectrical coordination of cell activity toward anatomical target states: an engineering perspective on regeneration, in Regenerative Engineering and Developmental Biology: Principles and Applications, David Gardiner ed., CRC Press, Florida, in press

Neuhof, M., Levin, M., and Rechavi, O., (2016), Vertically and horizontally-transmitted memories – the fading boundaries between regeneration and inheritance in planaria, Biology Open, 5, 1177-1188
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Baluska, F., and Levin, M., (2016), On Having No Head: Cognition throughout Biological Systems, Frontiers in Psychology, 7: 902, doi: 10.3389/fpsyg.2016.00902
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Sullivan, K. G., Emmons-Bell, M., and Levin, M., (2016), Physiological Inputs Regulate Species-Specific Anatomy During Embryogenesis And Regeneration, Communicative and Integrative Biology, 9:4, e1192733
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Edelstein, L., Fuxe, K., Levin, M., Popescu, B., and Smythies, J., (2016), Telocytes in their context with other intercellular communication agents, Seminars in Cell and Developmental Biology, 55:9–13
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Durant, F., Lobo, D., Hammelman, J., and Levin, M., (2016), Physiological controls of large-scale patterning in planarian regeneration: a molecular and computational perspective on growth and form, Regeneration, 3(2): 78-102
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Pezzulo, G., and Levin, M., (2015), Re-membering the body: applications of computational neuroscience to the top-down control of regeneration of limbs and other complex organs, Integrative Biology, 7: 1487-1517
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Lobo, D., and Levin, M., (2016), Computing a worm: reverse-engineering planarian regeneration, Advances in Unconventional Computing, Andrew Adamatzky ed., Vol. 2, Springer, p. 637-654

Bessonov, N., Levin, M., Morozova, N., Reinberg, N., Tosenberger, A., Volpert, V., (2015), Target morphology and cell memory: a model of regenerative pattern formation, Neural Regeneration Research, 10(12): 1901-1905
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Blackiston, D. J., Shomrat, T., and Levin, M., (2015), The Stability of Memories During Brain Remodeling: a Perspective, Communicative and Integrative Biology, 8(5): e1073424
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Levin, M., (2015), Nerves read the electrical topography of their microenvironment in making growth decisions, The Node
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Friston, K., Levin, M., Sengupta B., and Pezzulo, G., (2015), 'Knowing one's place' a free energy approach to pattern regulation, Journal of the Royal Society Interface, 12: 20141383
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Levin, M., (2014), Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo, Molecular Biology of the Cell, 25: 3835-3850
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Zhu, F., Skommer, J., Huang, Y., Akagi, J., Adams, D. S., Levin, M., Hall, C. J., Crosier, P. S., and Wlodkowic, D., (2014), Fishing on chips: up-and-coming technological advances in analysis of zebrafish and Xenopus embryos, Cytometry A, 85A: 921-932
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Mustard, J., and Levin, M., (2014), Bioelectrical mechanisms for programming growth and form: taming physiological networks for soft body robotics, Soft Robotics, 1(3): 169-191
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Hernandez-Diaz S., and Levin, M., (2014), Alteration of bioelectrically-controlled processes in the embryo: a teratogenic mechanism for anticonvulsants, Reproductive Toxicology, 47: 111-114
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Lobikin, M., and Levin, M., (2014), Endogenous bioelectric cues as morphogenetic signals in vivo, chapter 15 in The Fields of Cells, edited by D. Fels and M. Cifra, p. 283-302
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Pai, V., and Levin, M., (2014), Bioelectric Controls of Stem Cell Function, in Stem Cells, edited by F. Calegari and C. Waskow, CRC Press, Chapter 5, p. 106-145
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Levin, M., (2014), Endogenous bioelectrical networks store non-genetic patterning information during development and regeneration, Journal of Physiology, 592(11): 2295–2305.
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Lobo, D., Solano, M., Bubenik, G. A., and Levin, M., (2014), A linear-encoding model explains the variability of the target morphology in regeneration, Journal of the Royal Society Interface, 11: 20130918
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Levin, M., (2013), Remembrance of Brains Past, The Node
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Vandenberg, L., Lemire, J., and Levin, M., (2013), It's Never too Early to get it Right: A Conserved Role for the Cytoskeleton in Left-Right Asymmetry, Communicative & Integrative Biology, 6(6): e27155
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Chernet, B., and Levin, M., (2013), Endogenous voltage potentials and the microenvironment: bioelectric signals that reveal, induce, and normalize cancer, Journal of Clinical and Experimental Oncology, S1: doi:10.4172/2324-9110.S1-002
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Levin, M., (2013), Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities, WIREs Systems Biology and Medicine, 5(6): 657-676
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Vandenberg, L. N., and Levin, M., (2013), A unified model for left-right asymmetry? Comparison and synthesis of molecular models of laterality, Developmental Biology, 379: 1-15
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Adams, D. S., and Levin, M., (2012), Endogenous Voltage Gradients as Mediators of Cell-Cell Communication: Strategies for Investigating Bioelectrical Signals During Pattern Formation, Cell and Tissue Research, (2013) 352:95-­122
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Tseng, A-S., and Levin, M., (2012), Cracking the bioelectric code: probing endogenous ionic controls of pattern formation, Communicative and Integrative Biology, 6(1):1-8

Tseng, A-S., and M. Levin, (2012), Transducing bioelectrical signals into epigenetic pathways during tadpole tail regeneration, Anatomical Record, 295:1541-1551
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Levin, M., (2012), Morphogenetic fields in embryogenesis, regeneration, and cancer: non-local control of complex patterning, BioSystems, 109 (2012) 243­-261.
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Lobo, D., Beane, W., and Levin, M., (2012), Modeling planarian regeneration: a primer for reverse-engineering the worm, PLoS Computational Biology, doi: 10.1371/journal.pcbi.1002481
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Levin, M., and Stevenson, C., (2012), Regulation of Cell Behavior and Tissue Patterning by Bioelectrical Signals: challenges and opportunities for biomedical engineering, Annual Reviews in Biomedical Engineering, 14: 295-323
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Levin, M., (2012), Molecular bioelectricity in developmental biology: new tools and recent discoveries. BioEssays, 34(3): 205-217
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Levin, M. (2011), Endogenous bioelectrical signals in development, regeneration, and neoplasm, in Topical Talks: The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London.
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Levin, M. (2011), Left-Right Asymmetry in Embryonic Development: How epigenetic, biophysical forces and gene activity interplay to determine a major embryonic axis, in Topical Talks: The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London.
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Levin, M., (2011), Endogenous Bioelectric Signals as Morphogenetic Controls of Development, Regeneration, and Neoplasm, in The Physiology of Bioelectricity in Development, Tissue Regeneration, and Cancer, C. Pullar ed., CRC Press.
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Levin, M., (2011), The wisdom of the body: future techniques and approaches to morphogenetic fields in regenerative medicine, developmental biology, and cancer. Regenerative Medicine, 6(6): 667-673
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Vandenberg, L. N., and Levin, M., (2010), Far from solved: a perspective on what we know about early mechanisms of left-right asymmetry. Developmental Dynamics, 239: 3131-3146
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Levin, M. (2009), Bioelectric mechanisms in regeneration: Unique aspects and future perspectives. Seminars in Cell and Developmental Biology, 20: 543-556
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Levin, M., (2009), Errors of Geometry: regeneration in a broader perspective. Seminars in Cell and Developmental Biology, 20(6): 643-645
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Levin, M., (2009), Regeneration: recent advances, major puzzles, and biomedical opportunities. Seminars in Cell and Developmental Biology, 20(5): 515-516
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Levin, M., Sundelacruz, S., Levin M., Kaplan, D. L., (2009), Role of membrane potential in the regulation of cell proliferation and differentiation, Stem Cell Reviews, 5(3): 231-46
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Blackiston, D. J., K. McLaughlin, and Levin, M., (2009), Bioelectric controls of cell proliferation: ion channels, membrane voltage, and the cell cycle, Cell Cycle, 8(21): 3527-3536
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Oviedo, N., and Levin, M., (2008), The planarian regeneration model as a context for the study of drug effects and mechanisms, in Planaria: A Model for Drug Action and Abuse, Raffa RB & Rawls SM (eds), RG Landes Co.: Austin, pp. 95-104

Nicolas, C.L., Abramson, C.I., and Levin, M. (2008), Analysis of behavior in the planarian model, in Planaria: A Model for Drug Action and Abuse, Raffa RB & Rawls SM (eds), RG Landes Co.: Austin, pp. 83-94

Aw, S., and Levin, M., (2008), What's Left in Asymmetry?, Developmental Dynamics, 237: 3453-3464
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Oviedo, N., Nicolas, C. L., Adams, D. S., and Levin, M. (2008), Planarians: a versatile and powerful model system for molecular studies of regeneration, adult stem cell regulation, aging, and behavior, in Emerging Model Organisms, Cold Spring Harbor Press
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Tseng, A-S., and Levin, M., (2008), Tail regeneration in Xenopus laevis as a model for understanding tissue repair, Journal of Dental Research, 87(9): 806-816
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Aw, S., and Levin, M., (2008), Is left-right asymmetry a form of planar cell polarity?, Development, 136: 355-366
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Vandenberg, L., and Levin, M., (2008), Perspectives and open problems in the early phases of left-right patterning, Seminars in Cell and Developmental Biology, 20: 456-463
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Levin, M., Palmer, R., (2007), Left-right patterning from the inside out. BioEssays, 29: 271-287
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Levin, M., (2007), Gap junctional signaling in morphogenesis. Progress in Biophysics and Molecular Biology, 94 (1-2): 186-206
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Levin, M., (2007), Large-Scale Biophysics: Ion Flows and Regeneration. Trends in Cell Biology, 17(6): 262-271
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Ingber, D., and Levin, M. (2007), What lies at the interface of regenerative medicine and developmental biology? Development, 134: 2541-2547
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Oviedo, N., and Levin, M. (2007), Gap junctions provide new links in Left-Right patterning, Cell, 129: 645-647
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Levin, M., Lauder, J., and Buznikov, G., (2006), Of minds and embryos: serotonin signaling as a pre-nervous morphogenetic mechanism. Developmental Neuroscience, 28:171-185
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Levin, M., (2006), Is the Early Left-Right Axis like a Plant, a Kidney, or a Neuron? The Integration of Physiological Signals in Left-Right Asymmetry. Birth Defects Research (Part C), 78: 191-223
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Levin, M., (2005), Left-right asymmetry in embryonic development: a comprehensive review. Mechanisms of Development, 122(1): 3-25
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Levin, M., (2004), The embryonic origins of left-right asymmetry. Critical Reviews in Oral Biology and Medicine, 15(4): 197-206
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Adams, D. S., and Levin, M. (2004). Early Patterning of the Left/Right Axis. In Gastrulation: from cells to embryo (C. D. Stern, Ed.), pp. 403-417. Cold Spring Harbor, New York.
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M. Levin, (2003), Electromagnetic fields in morphogenesis. Bioelectromagnetics, 24: 295-315
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M. Levin, (2003), Motor protein control of ion flux is an early step in embryonic Left-Right asymmetry. BioEssays, 25(10): 1002-1010
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Levin, Michael, (2002), Gap-junctional communication and embryonic development. Journal of Membrane Biology, 185 (3): 177-192
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M. Mercola, and M. Levin, (2001), Left-Right asymmetry determination in vertebrates. Annual Review of Cell and Developmental Biology, 17: 779-805
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Levin, Michael, (2001), Asymmetry of Body and Brain: Embryological and Twin Studies. In: Smelser N, Baltes P (eds.) International Encyclopedia of the Social and Behavioral Sciences. Elsevier, Oxford, UK, pp. 853-9
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Levin, Michael, (1999), Twinning and embryonic left-right asymmetry. Laterality, 4(3): 197-208
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Levin, Michael, (1999), Left-right asymmetry in animal embryogenesis, in Advances in Biochirality, edited by G. Palyi, C. Zucchi, and L. Caglioti, ch. 12, p. 137-152, Elsevier: Amsterdam
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Levin, Michael, (1999), Endogenous electromagnetic fields and radiations in regeneration, development, and neoplasm, Proceedings of the First World Congress on the Effects of Electricity and Magnetism in the Natural World, Madeira, Portugal

Levin, Michael, (1998), Left-Right asymmetry and the chick embryo. Seminars in Developmental Biology, 9: 67-76
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Levin, Michael, and N. Nascone, (1997), Two models of initial Left-Right Asymmetry Determination. Medical Hypotheses, 49: 429-435
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Levin, Michael, (1997), Left-Right Asymmetry in Embryonic Morphogenesis. BioEssays, 19(4): 287-296
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Levin, Michael, (1995), Use of Genetic Algorithms to solve biomedical Problems. M.D. Computing, 12(3): 193-198
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Levin, Michael, Current and potential applications of bioelectromagnetics in medicine, (1993), ISSEEM Journal, 4(1): 77-87
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