Sergei Mirkin
Professor
Genetics and Molecular Biology

Curriculum Vitae

Education

• 1978 M.S. in Genetics, Moscow State University, Moscow, USSR
• 1983 Ph.D. in Molecular Biology, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, USSR
  Advisor - Prof. Roman B. Khesin

Employment History

• 1978-1983 Graduate Student - Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, USSR
  Advisor - Prof. Roman B. Khesin
• 1983-1988 Postdoctoral Fellow - Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, USSR
  Advisor - Prof. Maxim Frank-Kamenetskii
• 1988-1989 Group Leader - Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, USSR
• 1989-1990 Fogarty International Fellow - La Jolla Cancer Research Foundation, La Jolla, CA, U.S.A.
  Advisor - Dr. Terumi Kohwi-Shigematsu
• 1990-1996 Assistant Professor - Department of Genetics, University of Illinois at Chicago, Chicago, IL, U.S.A.
• 1996-2002 Associate Professor - Department of Molecular Genetics, University of Illinois at Chicago, Chicago, IL, U.S.A.
• 2002-2003 Professor - Department of Molecular Genetics, University of Illinois at Chicago, Chicago,IL, U.S.A.
• 2003-2006 Professor - Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, U.S.A.
• 2007-present White Family Professor of Biology - Department of Biology, Tufts University, Medford, MA, U.S.A.

Honors, Awards and Professional Activities

• Honors Master of Sciences Thesis, Moscow State University, 1978
• Honorary Diploma for the Best Work in Physical-Chemical Biology, USSR Academy of Sciences, 1985
• Research Committee, USSR Academy of Medical Sciences, 1988 -1989
• Research Committee, American Cancer Society, Illinois Division, 1993 -1996
• Editorial board, Gene Therapy and Molecular Biology 1997- present
• Member of the NIH/NICHD Special Emphasis Panel (2001), ad hoc member of the Neuroscience II study section (1999), ad hoc member of the NIH Biochemistry Study Section (2000, 2002), ad hoc member of the Molecular Genetics C study section (2005)
• American Society for Biochemistry and Molecular Biology, 2002 - present
• American Society for Microbiology, 2003 – present
• Editor for GENE, 2003 – present
• Guest Editor for ChemTracts - Biochemistry and Molecular Biology theme issues "Unstable Microsatellites in the Human Genome", Part 1 – December 2004, Part 2 – March 2005
• Session Chair at 14th Conversations in Biomolecular Dynamics, Albany, 2005
• International Advisory Board for Molecular Biology (Mosk), 2005 – present
• Managing Editor for Frontiers in Bioscience, 2005 - present

Invited Speaker at Scientific Meetings and Conferences

• International Conference "Recognition Studies in Nucleic Acids", 1989, Sheffield, U. K.
• FEBS Conference on Bioorganic Chemistry, 1989, Moscow, USSR.
• XI West Coast Chromatin and Chromosomes Meeting, 1989, Assilomar, U.S.A.
• XIII West Coast Chromatin and Chromosomes Meeting, 1991, Assilomar, U.S.A.
•  INSERM-NIH Conference "Antisence Oligonucleotides and Ribonucleases-H, 1992, Arcachon, France.
• XIV West Coast Chromatin and Chromosomes Meeting, 1992, Assilomar, U.S.A.
• International Symposium "Analysis of Structures of Biomacromolecules and Their Interactions with Environmental Cytotoxic Agents", 1993, Brno, Czech Republic.
• International Symposium "Pharmaceutical Design: Anti-sense, Triple Helix, Nucleic Acids Binding Drugs", 1994, Palo Alto, U.S.A.
• First International Antisense Conference of Japan, 1994, Kyoto, Japan.
• XVII West Coast Chromatin and Chromosomes Meeting, 1995, Assilomar, U.S.A.
• Gene Therapy and Molecular Biology International Conference, 1997, Crete, Greece
• DNA Replication and Transcription International Conference, 1998, Crete, Greece
• Banbury Conference "The Role of DNA Topology, Conformation and Associated Factors in Gene Expression", 1999, Cold Spring Harbor, U.S.A.
• 2nd International Conference on "Unstable Microsatellites and Human Disease", 1999, Chapel Hill, U.S.A.
• 4th International Conference on "Unstable Microsatellites and Human Disease", 2004, Banff, Canada.
• International Symposium "DNA Structure, Genomic Rearrangements and Human Disease", 2006, Houston, U.S.A.
• 5th International Conference on "Unstable Microsatellites and Human Disease", 2006, Granada, Spain.
• 28th Asilomar Chromatin and Chromosome Conference, 2006, Asilomar, U.S.A.
• 15th Conversations in Biomolecular Dynamics, 2007, Albany, U.S.A.
• Chromosome Dynamics Gordon Conference, 2007, Biddeford, U.S.A.

Invited Scientific Seminars

• Department of Molecular Biology, Princeton University, 1991
• Laboratory of Oncogenesis, NCI, Frederick, 1991
• Basic Sciences Division, Fred Hutchinson Cancer research Center, 1991
• Museum d'Histoire Naturelle, Paris, France, 1992
• SRI International, Menlo Park, 1992
• Department of Biochemistry, Northwestern University, 1992
• Department of Biochemistry, University of Alberta, Edmonton, Canada, 1993
• Department of Pharmacology, Mayo Clinic, Rochester, 1993
• Laboratory of Molecular Genetics, NIEHS, NIH, Research Triangle Park, 1993
• Department of Pharmacology, UMDNJ-Robert Wood Johnson Medical School, Piscataway, 1993
• Genetics and Biochemistry Branch, NIDDK, NIH, Bethesda, 1993
• Department of Biology, Iowa State University, 1994
• Nuclear Medicine Department, NIH, Bethesda, 1995
• Department of Biochemistry, Oklahoma State University, 1997
• Basic Science Division, Fred Hutchinson Cancer research Center, 1997
• Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany, 1997
• Department of Biochemistry, Mayo Clinic, Rochester, 1998
•  Department of Biochemistry, Northwestern University, Evanston, 1998
• Cancer Center, Northwestern University, Chicago, 1998
• Children Memorial Institute for Education and Research, 1998
• Department of Molecular Biology, Princeton University, 1999
• Division of Biology, Lawrence Berkeley National Laboratory, Berkeley, 1999
• Department of Biochemistry, University of Illinois at Urbana, 1999
• Laboratory of Molecular Genetics, NIEHS, NIH, Research Triangle Park, 1999
• Department of Microbiology, Wayne State University, 2000
• Institute des Hautes Etudes Scientifiques, Bures Sur Yvette, France, 2000
• Laboratory of Immunopathology, NIAID, NIH, Bethesda, 2001
• Jackson Laboratory, Bar Harbor 2001
• Institute of Biosciences and Technology, Texas A&M University, Houston 2002
• Pharmacology Seminar Series, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, 2003
• Genetics and Biochemistry Branch, National Institutes of Health, Bethesda 2003
• Gene Regulation and Chromosome Biology Laboratory, National Cancer Institute, Frederick 2004
• Genetic Task Force of Illinois, Chicago 2004
• Department of Molecular Biology, University of California, Berkeley 2004
• Joint Seminars in Molecular Biology, University of California, Davis 2004
• Department of Biochemistry & Molecular Biology, Wright State University, Dayton 2004
• Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock 2004
• Department of Biochemistry and Molecular Genetics, University of Alabama, Birmingham 2004
• Department of Biology, Tufts University, Medford 2005
• Department of Biochemistry, University of Illinois, Urbana 2005
• Eppley Institute for Cancer Research, University of Nebraska, Omaha 2006
• Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 2006
• School of Biology, Georgia Institute of Technology, Atlanta, 2006
• Department of Molecular Genetics & Microbiology, University of Florida, Gainesville 2006
• Centro de Investigaciones Biológicas, Madrid, Spain, 2006
• UT MD Anderson Cancer Center, Science Park, 2006
• Lutheran General Cancer Research Center, Chicago, 2007
• National Cancer Institute, Bethesda, 2007
• Marine Biological Laboratory, Woods Hole, 2007

Current Grant Support

• National Institutes of Health, 2R01GM060987 "Replication of simple DNA repeats", Principal Investigator, 2/1/01 - 1/31/09

Previous Grant Support

• National Science Foundation, MCB723924 "DNA triplexes and replication", Principal Investigator, 09/01/94 - 08/31/01.
• National Institutes of Health, 1RO1GM60987 "Transcriptionally-dependent rearrangements in DNA", Principal Investigator, 05/01/96 - 04/30/00.
• Council for Tobacco Research, #4468 "Trinucleotide repeats and replication", Principal Investigator, 01/01/97 – 12/31/99.
• National Institutes of Health, R55GM46405-01A1 "Triple-helical DNA in the TATA-less oncogene promoter", Principal Investigator, 10/1/92 - 9/30/94.
• American Cancer Society, MG-25 "Triple-helical DNA in oncogene promoters", Principal Investigator, 01/01/92 - 12/31/93.
• American Cancer Society Illinois Division, Inc., "The mechanism of DNA modification by chloroacetaldehyde", Principal Investigator, 9/28/90 - 9/27/92.

Teaching

University Service

Graduate Students Advised

• George M. Samadashwily, Ph.D. in 1996 - Currently at University of California
• Randal Cox, Ph.D. in 1997 - Currently at UIC
• Gordana Raca, Ph.D. in 2001 - Currently at Emory University
• Gerald Buldak, Ph.D. in 2004 - Currently at Loyola University
• Ekaterina Mirkin, Ph.D. in 2006 - Currently at Harvard University
• Irina Voineagu, 2004 - present

Postdoctoral Fellows Advised

• Andrew Dayn, Ph.D., 1990 -1993, UIC - Currently at Exigen, Inc.
• Ganapathirama Raghu, Ph.D., 1992 -1994, UIC - Currently at Pherin Pharmaceuticals
• Alexey Danilkovich, Ph.D., 1993 -1994, UIC - Currently at Russian Acad. Sci.
• Andrey Krasilnikov, Ph.D.,1996 - 2000, UIC - Currently at Penn State University
• Elena Siyanova, Ph.D., 1996 - 2000, UIC - Deceased
• Maria Krasilnikova, Ph.D., 1996 - 2005, UIC - Currently at Penn State University
• Alexander Shishkin, Ph.D. 2005 - present, Tufts
• Sylwia Szwarocka, Ph.D. 2007 - present, Tufts

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