Faculty & Research

Mitch McVey
Assistant Professor
Molecular Biology: Drosophila genetics and DNA repair

Publications

McVey, M., S. Andersen, G.J. Broze, and J.J. Sekelsky. 2007. Multiple roles for the Drosophila DmBlm helicase in maintenance of genome stability. Genetics 176: 1979-1992.

Rybarczyk, B.J., Baines, A.T., McVey, M., Thompson, J.T., and Wilkins, H.R. 2007. A case-based approach increases student learning outcomes and comprehension of cellular respiration concepts. Biochemistry and Molecular Biology Education 35: 181-186

McVey, M., D. Radut, and J.J. Sekelsky. 2004. End-joining repair of double-strand breaks in Drosophila is largely DNA ligase IV independent. Genetics 168: 2067-2076.

McVey, M., J.R. LaRocque, M.D. Adams, and J.J. Sekelsky. 2004. Formation of deletions during double strand break repair in Drosophila DmBlm mutants occurs after strand invasion. Proc. Natl. Acad. Sci. USA 101: 15694-15699.

McVey, M., M.D. Adams, J. LaRocque, and J.J. Sekelsky. 2004. Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila. Genetics 167: 699-705.

Baines, A.T., McVey, M., Rybarczyk, B., Thompson, J.T., and Wilkins, H.R. 2004. The mystery of the toxic flea dip: an interactive approach to teaching aerobic cellular respiration. Cell Biology Education 3: 62-68.

Adams, M.D., M. McVey (co-first author), and J.J. Sekelsky. 2003. Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing. Science 299: 265-267.

Park, U.P., M. McVey, and L. Guarente. 2002. Separation of mother and daughter cells. Methods in Enzymology 351:468-77.

Kaeberlein, M, Jeagalin, B, and M. McVey. 2002. AGEID: a database of aging genes and interventions. Mechanisms of Ageing and Development 123: 1115-1119.

Kaeberlein, M, M. McVey, and L. Guarente. 2001. Using yeast to find the fountain of youth. Science Aging Knowledge Environment Oct 3; 2001(1):pe1.

McVey, M., M. Kaeberlein, H.A. Tissenbaum, and L. Guarente. 2001. The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination. Genetics 157: 1531-1542.

Johnson, F.B., R.A. Marciniak, M. McVey, S.A. Stewart, W.C. Hahn, and L. Guarente. 2001. The Saccharomyces cerevisiae WRN homologue Sgs1p participates in telomere maintenance in cells lacking telomerase. EMBO Journal 20: 905-913.

Stone, E.M., C. Reifsnyder, M. McVey, B. Gazo, and L. Pillus. 2000. Two classes of sir3 mutants enhance the sir1 mutant mating defect and abolish telomeric silencing in Saccharomyces cerevisiae. Genetics 155: 509-522.

Kaeberlein, M., M. McVey (co-first author), and L. Guarente. 1999. SIR2/3/4 and SIR2 alone regulate life span in Saccharomyces cerevisiae by two different mechanisms. Genes and Development 13: 2570-80.

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