Biology 005 Neuroanatomy.
(Cross-listed as Occupational Therapy 103). Call Boston School of Occupational Therapy (627-5720) for information about this course. Call #00092

Biology 008 Human Heredity.
The basics of human genetics for students not majoring in the biological sciences. Cells and chromosomes, Mendelian genetics, sex-linkage, sex determination, what is a gene, genetic testing including forensics and pre-natal diagnosis, embryonic stem cells, genetically modified foods, cancer, genes and human behavior. The text is Human Heredity, 7^th ed. by M.R. Cummings (ISBN 0-534-49511-7 or ISBN 0-495-11308-5). Prerequisite: high school biology. Dr. Siegel Call #00083 Block D: Mon. 9:30-10:20am, Tues. & Thurs. 10:30-11:20am. Barnum 104.

Biology 010 Plants and Humanity.
(Cross-listed as Environmental Studies 10) Structure, activities, human and ecological significance of plants, including an overview of plant diversity. Emphasis placed on global aspects of this dynamic science, with selected topics on acid rain, deforestation, biotechnology, and other applications. Also covered are medicinal, poisonous, and nutritional sources from seaweeds and mushrooms to mangos and durians. Primarily for non-majors. Dr. Ellmore Call #00093 Block C: T-W-F 9:30-10:20. Barnum 008.

Biology 014L Organisms and Populations W/Lab.
Selected topics in, population biology, plant physiology, and animal physiology with emphasis on evolutionary mechanisms. Together with Biology 13L, this course forms the first-year core sequence for Biology majors. Prerequisite: Biology 3 or 13L are recommended, but the Biology 13L-14L sequence can be completed in reverse order. Three lectures and one laboratory each week. Drs. Chew, Ellmore & Bernheim . Call #00108 Block D: M - 9:30-10:20, T & TH 10:30-11:20. Cohen Aud. View Library Research site for Bio 14.

Labs A, C, E, H, I, K in Barnum 200; Labs B, D, F, G, J, L in Barnum 216.
Biology 14L Optional review session Call #00106. Wed., 5:30-6:20, Barnum 008.

Biology 14WW Optional Writing Workshop.
Help take control of the demands of large science courses by joining a workshop of Bio 14 students using writing to focus, reflect, and expand their involvement in biology. Writing Workshop provides the advantage of putting more attention on Bio. 14 without doing extra work for a grade. We meet once a week, using in-class writing to highlight linkages between lecture topics, focus study efforts, organize laboratory write-ups, and more. If you’re interested in bringing biology to the front of your thoughts at least once a week, join the active cohorts of Bio. 14L WW—the writing workshop. Pass/Fail Must be enrolled in Bio 14L. Freshmen & Sophomores especially welcome. Dr. Chew Call #00107. Block K: Wednesday, 4:30-5:20. Barnum 008.

Biology 016 Bioscience Challenge Seminars.
An introductory seminar for freshmen and sophomores to explore topics in the biosciences. Includes seminars given by Tufts researchers to introduce students to research being conducted at the various Tufts campuses. Students will be introduced to data analysis and we will also read and discuss a book of current interest, a paper from the scientific literature and research ethics. Twelve weekly sessions. 1/2 course credit, pass-fail grading. Prerequisite: concurrent enrollment in an introductory biology or other natural science course. Dr. Feldberg. Call #00109. Block L+ Tues., 4:30-5:45 Barnum 114. Pass/Fail only.

Biology 046 Cell Biology.
Basic concepts of cellular organization, function, regulation. Emphasis on cell structure and microscopy, plasma membrane functions such as transport, secretion, and endocytosis, the extracellular matrix, signal transduction, the cytoskeleton and cell growth and division. Three lectures. Prerequisites: Biology 13 or equivalent required. (Group A). Dr. Lynch Call # 00110. Block E+: M-W 10:30-11:45. Barnum 104.

Biology 050A&B Experiments in Molecular Biology.
Similar to Biology 49, but investigating a series of laboratory problems using modern techniques of biotechnology. Gene cloning, recombinant protein expression, protein biochemistry, and immunochemistry are emphasized for teaching state of the art laboratory skills and for reinforcing basic concepts of modern molecular biology. One laboratory session per week plus one discussion period. Prerequisites: Bio 13L and sophomore standing, or consent. Open only to majors in biology, biochemistry, or chemical engineering. Drs. Fuhrman, Freudenreich & Gaudette. Call # 00111. Section A: Monday 1:20-5:30pm. Call #00000 Section B: Wednesday 1:20-5:30pm, Barnum 001. Lecture for Sections A and B: Thursday 3:00-3:50, Barnum 114.

Biology 050-WW Experiments in Molecular Biology Writing Workshop option.
Must be enrolled in Bio 50 concurrently. No course credit. Pass/Fail. Dr. Fuhrman Call # 00112. Thurs 1:30-2:20, Barnum 113.

Biology 052 Experiments in Cell Biology.
Cells are the smallest structures capable of basic life processes. The field of Cell Biology focuses on examining cells and the behaviors they perform. This course will introduce students to the investigation of several laboratory problems using standard techniques of cell biology. Since there are numerous techniques employed by researchers in this exciting field, this semester there will be an emphasis on the following procedures/concepts: microscopy, cell signaling/regeneration, chromatography, and subcellular fractionation. Students also design and conduct an experiment of their own design. Prerequisites: sophomore standing and Biology 13 or equivalent. Dr. Lynch Call #00113. Thurs 12:30 – 4:30. Barnum 001.

Biology 094 Introduction to Research.
At least ten hours per week of guided laboratory research. Students enrolling in this course should have two half-days free or one full day free in their course schedules. Details of individual project to be arranged with the research sponsor. Provides students with opportunity to participate in biological research on the Tufts Medford and Boston campuses. Cannot be counted as one of the eight graded courses required for a biology major or as a laboratory requirement. A written report by the student and a written evaluation by research sponsor are required. Does not count toward Biology major or lab requirement. In order to register for this course you must see the director of undergraduate research in the Biology Department. Refer to “Blackboard” site for additional information and forms for this course. Prerequisites: Completion of one biology course beyond the level of Bio. 13, 14. Prior consent of course coordinator – Dr. Lynch Call # 00114 Pass/Fail

Biology 105 Molecular Biology.
Fundamentals of recombinant DNA technology. Mechanisms of DNA replication, recombination and transcription, gene structure and function in prokaryotes and eukaryotes are emphasized. Advanced topics including the biology of mobile DNA, the molecular basis of genetic diseases, retroviral infection, and chromatin based gene regulation are based on current literature. Prerequisite: Biology 41 or equivalent. (Group A) Dr. McVey Call # 00118. Block D+: Tues. & Thurs. 10:30-11:45. Barnum 114. Optional Recitation: Call #00117 Monday 9:30-10:20. Barnum 114.

Biology 106 Microbiology W/Lab.
A survey designed to give a general understanding of bacteria and viruses. Bacterial structure, growth, metabolism, evolution, ecology, and pathogenic mechanisms and viral reproductive cycles. The laboratory will familiarize students with microbiological methods and various groups of microorganisms. The texts are a lab manual, Microbiology Laboratory Theory and Application.2^nd ed. (ISBN 0-89582-708-5), and Brock Biology of Microorganisms, the 11^th ed. (ISBN 0-13-219226-8 or ISBN 0-13-196893-9 or ISBN 0-13-144329-1). A less expensive online subscription to the 11^th ed. is also available. Two lectures, one laboratory per week. (Group A) Prerequisites: Three biology courses and Chemistry 2. Dr. Siegel Call # 00120. Block G+: M & W 1:30-2:45. Barnum 114. Call # 00119 Lab-Biology 106-LA Block 6+ Tues. 1:20-4:20. Barnum 001. 1.5 credits.

Biology 118 Plant Physiology.
Interaction of living plant components performing biological functions including water transport, mineral uptake, movements, and signaling between plant parts in response to environmental cues. (Group B) Prerequisites: Bio. 13 & 14 or equivalent. Dr. Ellmore Call #00121 Block F+: T & TH 12:00-1:15. Barnum 114.

Biology 130 Animal Behavior.
An examination of ethological theory: the development of behavior, orientation, migration, communication, and social behavior. Particular emphasis will be placed on the functioning of animal societies. Prerequisites: Biology 13 and 14, or equivalent. (Group C). Prerequisite: Biology 13/14 or equivalent. Dr. Starks Block B: Tues, Thurs, Fri, 8:30-9:20AM, Barnum 104. Call #00124.

Biology 131 Principles of Medical Imaging
(Cross listed as Electrical Engineering 131 and Biomedical Engineering 131). Call the Dept. of Electrical Engineering and Computer Science, 7-2336 for additional information about this course. This course covers the basic physical principles and the design of the instrumentation for the most common medical imaging techniques. Covered areas include diagnostic ultrasound, radiography, computed tomography, positron emission tomography (PET), single photon emission computed tomography (SPECT), and magnetic resonance imaging (MRI). The principles behind each imaging modality are used to guide the interpretation of representative diagnostic images. Dr. Fantini. Call #00125.

Biology 134 Neurobiology.
Biology of nervous systems. From the biophysical basis of neuronal function, through synaptic interactions and signal processing in neural circuits, to behavior, learning and memory. Examples from both vertebrates and invertebrates. Prerequisites: Biology 13 and 14, plus one Group A course in biology or Psychology 103. (Group B) Dr. Trimmer Call # 00112. Block E: M-W-F 10:30-11:20am. Barnum 114.

Biology 144 Conservation Biology.
Learning and application of principles from population ecology, population genetics, and community ecology to the conservation of species and ecosystems. Focus will be on rare and endangered species, as well as threatened ecosystems. Also includes applications from animal behavior, captive breeding, and wildlife management. (Group C) Prerequisite: Biology 14, or equivalent. Dr. Reed Call #00127. Block G+: M+W 1:30-2:45. Barnum 104.

Biology 144WW Optional Writing Workshop.
Pass/Fail. Must be enrolled in Bio 144, Conservation Biology. Dr. Reed. Call #00126. Block I: Monday 3:00-3:50. Barnum 113.

Biology 152 Biochemistry and Cellular Metabolism.
Survey of the structure and function of the molecules involved in life processes. Chemical and physical properties of proteins, carbohydrates, and lipids; enzyme kinetics and the mechanism of enzyme action; metabolic pathways of carbohydrates and lipids. Three lectures. Prerequisites: Biology 13 and Chemistry 50 or 51. (Group A) Dr. Feldberg & Dr. Gaudette Call # 00128 Block D: Monday 9:30-10:20am, Tues +Thurs 10:30-11:20. Barnum 008.

Biology 164 Marine Biology.
An intermediate-level introduction to the biology of marine organisms. Following a detailed survey of marine animal and plant groups, the course will consider aspects of biology that are particularly relevant to marine organisms: bioluminescence and its ecological significance, locomotory mechanics, food-chain dynamics, migration and dispersal, biological invasions, the effects of pollution, and the design and creation of marine protected areas. Prerequisites: Biology 13 and 14 or equivalent. (Group C) Dr. Pechenik Call # 00129 Block C: T-W-F 9:30-10:20. Barnum 104.

Biology 172 Biochemistry II.
(Cross listed as Chem 172) See Chemistry for details. Dr. Lee Call #00130 Block B+: Tues & Thurs. 8:05am-9:20am.

Biology 177WW Seminar in Inflammation.
Study of processes involved in mammalian inflammatory reactions. Reading and discussion of the current literature will be emphasized. Selected topics include leukocyte chemotaxis and phagocytosis, generation and actions of inflammatory mediators, allergic reactions, autoimmune diseases, and basic immunologic processes. (Group A) Prerequisite: consent. Dr. Cochrane Call #00131. Block ARR: Tues 3:00-4:15, Thurs. 3:00-5:20pm. Barnum 113.

Biology 178 Seminar in Immunology.
Advanced topics in immunology. Readings and discussion of the current literature emphasized. Topics include antigen presentation. T-cell activation, cytokine release and effects, self- and non-self recognition, and immunopathology of HIV. (Group A) Prerequisite: Bio 104 or equiv. Dr. Bernheim Call#00132. Block 8: Thurs., 1:30-4:00. Barnum 006.

Biology 187 Mammalian Central Nervous System with laboratory.
Functional organization of the Human Brain and Spinal cord, including cellular structure, functional circuitry and behavioral correlates, and gross anatomy. Emphasis on areas of current research. Lecture- laboratory/demonstration sessions. May not be applied toward fulfillment of the laboratory requirement in biology. In addition to classroom lectures and discussions and a trip to the Gross Anatomy Lab (for those who want to come), I will assign for review and discussion movies with involvement of the Central Nervous System/Hollywood on the Brain: Forbidden Planet, Fantastic Voyage, Memento, Terminal Man, Young Dr. Frankenstein, 50 First Dates, and Being John Malkevich. I welcome any other suggestions for movies to view. (they will be on reserve at Tisch). I will provide the textbook-Integrated Neuroscience by EMMarcus and S Jacobson. There will be a midterm and a final exam. (Group B) Prerequisites: Biology 13 and 14, junior standing, and consent of instructor. Dr. Jacobson. (stan.jacobson@tufts.edu)Call # 00134. Block 3: Thursday 9:00-11:30. Barnum 208.

Biology 194 Independent Research.
The department feels that the 8 biology courses required for the major should be well distributed in the field of biology. Therefore, normally one course in Biology 193, 194 will be accepted as one of these 8. The student may take courses in Biology 193, 194 beyond these limitations and count them for credit toward graduation but not toward the biology major. One course under 193, 194 can be used to fulfill the biology department requirement for laboratory courses. One week before the last day of classes the student must deliver to his/her sponsor and members of the 193/194 review committee (4 faculty members) copies of a paper concerning his or her semester's work. This should follow the format of a scientific paper. During the reading period following the last class of the semester, the student will meet with this same review group to present and discuss his/her work, and they will jointly award the grade for the course. The presentation should be a 10-15 minute review of the work already described in the written summary followed by questions, discussion of details, etc., lasting another 15 minutes. The exact time for each session will be posted prior to the end of classes. The oral presentation will be open to all interested faculty and students. Normally 15 hours per week in the laboratory equals one course credit. The grade is based upon the intellectual quality of the work. Prerequisite: Bio 93 or comparable experience. To register for this course you must see the director of undergraduate research in the Biology department. See Blackboard site for additional information and required forms. Prior consent of Coordinator- Dr. Lynch. Call # 00136.

Biology 194T Honors Thesis Research.
Intensive laboratory or field investigation, including independent design of experiments, a written thesis, and an oral defense. (See notes above under Biology 194). Normally, a student applies during his/her sixth semester and should have a cumulative grade average of at least 3.30 including at least three A's in Biology. Prerequisite: Biology 193T. Dr. Lynch. Call #00135 In order to register for this course you must see the director of undergraduate research in the Biology department. In addition, you must have registered with Carol Downing in Dowling Hall by the middle of September. These two steps are essential. Without completing them you are not registered. See Blackboard for additional information and required forms.

Biology 196-01 Biology of Marine Fishes.
This upper-level survey course covers the evolution, systematics, anatomy, physiology and behavior of fishes from temperate to tropical environments. The course also examines the diversity of fish interactions in aquatic communities: predator/prey relationships, host/symbiont interactions, and the various roles of fishes as herbivores. Study of inter and intra-specific predator-prey relationships among fish populations in aquatic communities integrates principles of ecology. (Group C) Prerequisites: 1 year general biology and one upper level biology course. Limited to undergrad biology majors. 1 course credit. Visit web site for more info: http://www.brandeis.edu/marinestudies/courses.html. HIGH DEMAND Must register for class in Biology Department. January 22–May 7, Tuesdays 5-9:00 p.m. Class meets at the N.E. Aquarium in Boston. Max. of 6 students. Call #00137.

Biology 196-02 DNA: Structure to Function.
DNA structure and functioning studied through a combination of lectures and discussions of the original papers. DNA is the sine qua non molecule of life. Originally, it was believed to be a uniform right-handed double helix with limited structural flexibility. It has now become clear, however, that DNA structure is highly versatile, and this versatility is central for major genetic processes. The first half of the course will consider DNA secondary and tertiary structures, DNA topology and topoisomerases, the mechanisms of protein-DNA recognition and the structure of the chromatin. The second half of the course will emphasize how the principles of DNA organizationare employed in key genetic transactions, including DNA replication, transcription, repair and recombination. Prerequisites: Biology 41 and permission of the instructor. Call #00138. Dr. Mirkin Block H+: Tues & Thurs. 1:30-2:45. Barnum 114.

Biology 244 Graduate Seminar in Evolutionary Ecology.
Call #00000. Dr. Lewis Block 6: Tuesday 1:30 – 4:00. Barnum 207. Graduate standing and permission.

Biology 291 Graduate Seminar in Molecular Biological Research.
Call #00141. Dr. Freudenreich Block ARR: Thursday 8:30-10:20am. Barnum 113. Prior consent required.